Article

Integrated single cell analysis of human lung fibrosis resolves cellular origins of predictive protein signatures in body fluids

2020-01-27

Abstract excerpt

Single cell genomics enables characterization of disease specific cell states, while improvements in mass spectrometry workflows bring the clinical use of body fluid proteomics within reach. The correspondence of cell state changes in diseased organs to peripheral protein signatures is currently unknown. Here, we leverage single cell RNA-seq and proteomic analysis of large pulmonary fibrosis patient cohorts to ide...

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Literature Corpus work: affa698a-86ea-5cc4-aa90-af5cee9c604a
DOI: 10.1101/2020.01.21.20018358

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