Article

Folic Acid Supplementation in Children with Sickle Cell Disease: Study Protocol for a Double-Blind Randomized Cross-Over Trial

2020-05-22

Abstract excerpt

<title>Abstract</title> <p>• <bold>Background</bold>: Sickle cell disease (SCD) is a genetic disorder which causes dysfunctional red blood cells (RBC) and is thought to increase requirements for folate, an essential B-vitamin, due to increased RBC production and turn-over in the disease. High-dose supplementation with 1-5mg/d folic acid, synthetic folate, has been the standard recommendation for children with SCD...

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Literature Corpus work: afe8d44d-7103-5e02-882e-2e3f0bf0974e
DOI: 10.21203/rs.3.rs-30458/v1

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