Dissociation of Striosome and Matrix Activation in the Human Striatum During the Cue and Execution Phases of Working Memory

Abstract excerpt

The striatum comprises two neurochemically and anatomically distinct tissue compartments, the striosome and matrix, that are hypothesized to support different aspects of cognition and action. In animal studies, the striosome has been linked to reward evaluation, emotional learning, and decision-making under conflict, whereas the matrix is more closely associated with sensorimotor integration and task execution. Ho...

Topics

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• Dopamine and cAMP-Regulated Phosphoprotein 32
• Image Processing, Computer-Assisted
• Imaging, Three-Dimensional
• Memory Disorders
• Memory, Short-Term
• Mental Recall
• Receptors, Dopamine D2
• Verbal Learning

Identifiers and source

Literature Corpus work

af827e20-eefe-5fd5-b89b-938694645749

DOI

10.64898/2026.01.29.702581