Article

A Qualitative Transcriptional Signature for the Histological Reclassification of Lung Squamous Cell carcinomas and Adenocarcinomas

2019-08-14

Abstract excerpt

<h4>Background: </h4> Targeted therapy for non-small cell lung cancer is histology dependent. However, histological classification by routine pathological assessment with hematoxylin-eosin staining and immunostaining for poorly differentiated tumors, particularly those from small biopsies, is still challenging. Additionally, the effectiveness of immunomarkers is limited by technical inconsistencies of immunostaini...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: af4f428f-75f7-5852-8d10-6d47675a1172
DOI: 10.21203/rs.2.9782/v2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A Qualitative Transcriptional Signature for the Histological Reclassification of Lung Squamous Cell carcinomas and AdenocarcinomasDOI 10.21203/rs.2.9782/v2Read

A qualitative transcriptional signature to reclassify histological grade of ER-positive breast cancer patientsSemantic proximity Read

The utility of the proposed IASLC/ATS/ERS lung adenocarcinoma subtypes for disease prognosis and correlation of driver gene alterations.Semantic proximity Read

Molecular differences across invasive lung adenocarcinoma morphological subgroupsSemantic proximity Read

Validation of the Novel International Association for the Study of Lung Cancer Grading System for Invasive Pulmonary Adenocarcinoma and Association With Common Driver Mutations.Semantic proximity Read

Clinically Relevant Characterization of Lung Adenocarcinoma Subtypes Based on Cellular Pathways: An International Validation StudySemantic proximity Read

A Five-Gene and Corresponding Protein Signature for Stage-I Lung Adenocarcinoma PrognosisSemantic proximity Read

A gene expression‐based single sample predictor of lung adenocarcinoma molecular subtype and prognosisSemantic proximity Read

Consensus of gene expression phenotypes and prognostic risk predictors in primary lung adenocarcinoma.Semantic proximity Read

Real-world applications of the new grading system in lung adenocarcinoma: A study of 907 patients focusing on revealing the relationship between pathologic grade and genetic status.Semantic proximity Read

Gene Expression Signature Differentiates Histology But Not Progression Status of Early-Stage NSCLCSemantic proximity Read

Development and Validation of a Prognostic Gene-Expression Signature for Lung AdenocarcinomaSemantic proximity Read

Identification of a novel prognostic gene signature in high-grade lung neuroendocrine tumorsSemantic proximity Read