Development and Validation of a Prognostic Gene-Expression Signature for Lung Adenocarcinoma

Abstract excerpt

Although several prognostic signatures have been developed in lung cancer, their application in clinical practice has been limited because they have not been validated in multiple independent data sets. Moreover, the lack of common genes between the signatures makes it difficult to know what biological process may be reflected or measured by the signature. By using classical data exploration approach with gene...

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