Article

Computational drug repurposing identifies <i>N</i> -acetylglucosamine as a potential therapeutic compound for CLN3 Batten disease

2026-05-15

Abstract excerpt

Batten disease, also known as neuronal ceroid lipofuscinoses, is one of the most common causes of childhood dementia. It is characterized by the accumulation of lipofuscin in lysosomes, leading to loss of brain cell function, onset of dementia-like symptoms, vision loss and seizures and has extremely limited treatment options. Here, we performed computational drug repurposing analysis to identify existing compound...

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Literature Corpus work: af2e0b46-7c13-5ce3-a2c6-68fa448f5b2f
DOI: 10.64898/2026.05.12.724723

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