Article

Ionic regulation of Gram-positive phage adsorption governs host range and improves phage isolation efficiency

2026-03-09

Abstract excerpt

Antimicrobial-resistant Staphylococcus aureus and S. epidermidis remain major causes of invasive infection, yet isolation of therapeutically robust lytic phages targeting Gram-positive pathogens is often constrained by adsorption barriers imposed by thick peptidoglycan cell walls. We demonstrate that these limitations are primarily methodological. By optimising the ionic microenvironment during isolation through...

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Literature Corpus work: aecba31c-5794-501b-938c-aa20059d12c1
DOI: 10.64898/2026.03.09.706807

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