Article

Weakly supervised contrastive learning predicts tumor infiltrating macrophages and immunotherapy benefit in breast cancer from unannotated pathology images

2023-04-30

Abstract excerpt

The efficacy of immune checkpoint inhibitors is significantly influenced by the tumor immune microenvironment (TIME). RNA sequencing of tumor biopsies or surgical specimens can offer valuable insights into TIME, but its high cost and long turnaround time seriously restrict its utility in routine clinical examinations. Several recent studies have suggested that ultra-high resolution pathology images can infer cellu...

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Literature Corpus work: aeb87d09-8a90-5237-a299-7eea09ba30e0
DOI: 10.1101/2023.04.30.538851

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