Effects in descendant mice after generational low dose-rate 137Cs internal exposure

Abstract excerpt

How does chronic low-dose internal exposure to Cesium-137 radiation over multiple generations affect offspring? In this study, we sought to infer the effects on humans from experiments on mice, whose spontaneous mutation rate in the next generation is very similar to that of humans. Cesium-137 water (100 Bq/mL) was provided as drinking water to A/J mouse strains for chronic, low-dose, and low-dose-rate internal ex...

Topics

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• Abnormalities, Drug-Induced
• Fetal Death
• Genomic Instability
• Mammals
• Maternal Exposure
• Mutation
• Neoplasms
• Neoplasms, Radiation-Induced

Identifiers and source

Literature Corpus work

aea32e39-a25d-5071-b873-53ab6a60f1c4

DOI

10.21203/rs.3.rs-3692094/v1