Article

Plasma neurofilament light chain is elevated in Niemann-Pick Type C but glial fibrillary acidic protein is not

2023-12-16

Abstract excerpt

<h4>ABSTRACT</h4> <h4>OBJECTIVE</h4> Niemann-Pick Type C (NPC) is a genetic neurodegenerative lysosomal storage disorder commonly associated with psychiatric symptoms and delays to accurate diagnosis and treatment. This study investigated biomarker levels and diagnostic utility of plasma neurofilament light chain (NfL) and glial fibrillary acidic protein (GFAP) in NPC compared to healthy controls. <h4>METHODS</h4>...

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Literature Corpus work: ae5ac154-5d95-5f05-95e3-b235d1eae036
DOI: 10.1101/2023.12.12.23299884

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