Article

Actual Clinical Efficacy of Statin Therapy (Hmg-CoA Reductase Inhibitors) on the Course of SARS-Cov-2/COVID-19 Infection During the Domination Period of Alpha, Beta, Gamma and Delta Variants

2024-10-30

Abstract excerpt

To date, SARS Cov-2 virus has caused more than 775 million cases worldwide and led to 7 million deaths. The virus enters cells with the aid of the ACE2 receptor located in the airway epithelium, but also in endothelial cells lining the inner walls of vessels. Endothelial damage results in impaired blood flow and gas exchange. Statins have been shown to have a pleiotropic effects on the vascular epithelium. Aim of...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ae3add01-27a4-5c63-9011-c0acab9c96c2
DOI: 10.20944/preprints202410.2297.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Actual Clinical Efficacy of Statin Therapy (Hmg-CoA Reductase Inhibitors) on the Course of SARS-Cov-2/COVID-19 Infection During the Domination Period of Alpha, Beta, Gamma and Delta VariantsDOI 10.20944/preprints202410.2297.v1Read

Protective effects of statins on COVID-19 risk, severity and fatal outcome – a nationwide Swedish cohort studySemantic proximity Read

Hospital mortality in COVID-19 patients in Belgium treated with statins, ACE inhibitors and/or ARBsSemantic proximity Read

Therapeutic Combinations in Mild or Moderate COVID-19 to Reduce Nasopharyngeal Carriage of SARS-CoV-2 and Prevent Severe COVID-19 in Côte D’Ivoire: A Pragmatic Phase IIb Randomized Controlled Clinical Trial. The ANRS COV01 INTENSE-COV TrialSemantic proximity Read

Current status and clinical outcomes of pharmacotherapies according to SARS-CoV-2 mutations in patients with mild-to-moderate COVID-19: a retrospective single center study.Semantic proximity Read

Host - virus - drug interactions as determinants of COVID-19's phenotypes: A data-driven hypothesis.Semantic proximity Read

Molecular mechanisms of Thalidomide effectiveness on COVID-19 patients explained: ACE2 is a new ΔNp63α target geneSemantic proximity Read

Prevalence use of nonsteroidal anti-inflammatory drugs in the general population with COVID-19 and associated COVID-19 risk, hospitalization, severity, death, and safety outcomes: A systematic review and meta-analysisSemantic proximity Read

Currently prescribed drugs in the UK that could up or downregulate ACE2 in COVID-19 disease: A systematic reviewSemantic proximity Read

Hypertension in patients hospitalized with COVID-19 in Wuhan, China: A single-center retrospective observational studySemantic proximity Read

Exploring drugs and vaccines associated with altered risks and severity of COVID-19: a UK Biobank cohort study of all ATC level-4 drug categoriesSemantic proximity Read

SARS-CoV-2 Infection and Long-Term Risk of Cardiovascular and Renal MorbiditySemantic proximity Read

A Randomized Open-Label Trial To Evaluate The Efficacy And Safety Of Triple Therapy With Aspirin, Atorvastatin, And Nicorandil In Hospitalised Patients With SARS Cov-2 Infection: A Structured Summary Of A Study Protocol For A Randomized Controlled TrialSemantic proximity Read