Article

Canagliflozin Alleviates Diabetic Cardiovascular Disease via Lipid Lowering, Mitochondrial Homeostasis, and Gut Microbiota Regulation

2021-08-12

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Type 2 diabetes mellitus (T2DM) is associated with cardiovascular disease (CVD). Sodium glucose cotransporter 2 inhibitors (SGLT2i) represent the most effective oral drugs for the treatment of T2DM, and have been shown to improve generalized vascular dysfunction. However, it’s effect on improving diabetic CVD and the possible action mechanism are currently uncle...

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Literature Corpus work: ae393b01-2567-5174-b9cf-3b41cd9340c0
DOI: 10.21203/rs.3.rs-754308/v1

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