Analysis of the correlation between the expression of non-classical E2F transcription factor 8 (E2F8) in pan-cancer and prognosis and immune infiltration

Abstract excerpt

Despite emerging cell-or animal-based evidence supporting a relationship between E2F8 and cancer, a pan-cancer analysis has not been performed. By integrating various databases containing transcriptome, prognosis, and immune-related data, such as gene expression matrices, this study utilized the ESTIMATE algorithms and R program package to comprehensively investigate the pathogenic implications of E2F8 in diverse...

Topics

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• CD4-Positive T-Lymphocytes
• CD8-Positive T-Lymphocytes
• Central Nervous System Neoplasms
• E2F Transcription Factors
• Immune System
• Protein Interaction Mapping
• RNA-Seq
• Tumor Microenvironment

Identifiers and source

Literature Corpus work

ad63b4db-b377-52a3-8ec2-a5abf950cf66

DOI

10.21203/rs.3.rs-2899237/v1