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Augmentation of Omicron pathogenicity in hamsters using intratracheal inoculation

2023-10-09

Abstract excerpt

The Omicron variant of SARS-CoV-2 displays an attenuated phenotype in the Syrian hamster after intranasal inoculation. This is characterized by reduced viral replication and lung pathology in the lower respiratory tract. Here, we report that intratracheal inoculation with BA.1 Omicron recovers the lower respiratory tract replication and pathogenicity as observed with other lineages.

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Literature Corpus work
ad20f179-60cd-5d6e-96ef-5249471285d4
DOI
10.21203/rs.3.rs-3398781/v1
Open publication

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Augmentation of Omicron pathogenicity in hamsters using intratracheal inoculationDOI 10.21203/rs.3.rs-3398781/v1
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