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Patients with fibrosis from non-alcoholic steatohepatitis have heterogeneous intrahepatic macrophages and therapeutic targets

2023-02-23

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background and Aims</h4> In clinical trials for reducing fibrosis in NASH patients, therapeutics that target macrophages have had variable results. We evaluated intrahepatic macrophages in patients with non-alcoholic steatohepatitis to determine if fibrosis influenced phenotypes and expression of CCR2 and Galectin-3. <h4>Approach & Results</h4> We used nCounter to analyze liver biopsies from...

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Literature Corpus work
ac04991e-14c8-5ed9-88fa-8f1ef5031375
DOI
10.1101/2023.02.16.23285924
Open publication

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Patients with fibrosis from non-alcoholic steatohepatitis have heterogeneous intrahepatic macrophages and therapeutic targetsDOI 10.1101/2023.02.16.23285924
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