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Development and Validation of a Basement Membrane Inflammatory Response Gene Signature in Lung Adenocarcinoma

2025-04-02

Abstract excerpt

<title>Abstract</title> <p>Inflammatory cell infiltration within the tumor microenvironment compromises the basement membrane’ integrity, contributing to chemotherapy resistance and distant metastasis. This study investigates the interplay between inflammatory responses and basement membrane-related genes (BMIRGs) in lung adenocarcinoma (LUAD). With datasets from the TCGA and GEO databases, the BMIRG risk-score m...

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Literature Corpus work
abe4f15a-1550-5d57-be6b-798e889f15fa
DOI
10.21203/rs.3.rs-5637719/v1
Open publication

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