Establishment and validation of an immune-associated signature in lung adenocarcinoma.

doi:10.1016/j.intimp.2020.106867

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Article

Establishment and validation of an immune-associated signature in lung adenocarcinoma.

International immunopharmacology - 1 Nov 2020

Wang Zhenyu, Chen Xiaoman

Abstract excerpt

Recent studies demonstrated that immune associated genes (IAGs) played an important role in the treatment of lung adenocarcinoma (LUAD). In the research, we established an IAGs signature and validated its prognostic value in LUAD by using bioinformatic methods and public databases. Based on the RNA-Seq samples from The Cancer Genome Atlas (TCGA), 576 differentially expressed IAGs were firstly identified. The R...

Topics

Adenocarcinoma of Lung
Aged
Biomarkers, Tumor
Computational Biology
Databases, Genetic
ErbB Receptors
Female
Gene Expression Regulation, Neoplastic
Humans
Kaplan-Meier Estimate
Lung Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lymphocytes, Tumor-Infiltrating

Male

Middle Aged

Mutation

Neoplasm Staging

Nomograms

ROC Curve

Source

Open in PubMed

Identifiers

PMID: 32799112
DOI: 10.1016/j.intimp.2020.106867

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