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Gene–environment interaction in neurodevelopmental disorders: Setd5 haploinsufficiency and prenatal carbon nanoparticle exposure synergistically induce ASD-like phenotypes in male mice

2025-05-05

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Perinatal exposure to fine particles increases the risk of autism spectrum disorder (ASD). Thus, to prevent exposure-related neurodevelopmental disorders, it is crucial to clarify how such particles influence ASD susceptibility. However, replicating ASD-like behaviors in animal models using realistic low-dose particle exposure remains challenging, impeding progre...

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Literature Corpus work
ab1c2df2-6e73-5d41-8ddf-260ac50db1d8
DOI
10.21203/rs.3.rs-6530387/v1
Open publication

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Gene–environment interaction in neurodevelopmental disorders: Setd5 haploinsufficiency and prenatal carbon nanoparticle exposure synergistically induce ASD-like phenotypes in male miceDOI 10.21203/rs.3.rs-6530387/v1
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