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Article

Identification of prognostic signatures of ferroptosis and autophagy-dependent lipid metabolism-related genes in hepatocellular carcinoma

2025-05-05

Abstract excerpt

<title>Abstract</title> <p>The regulatory role of ferroptosis and autophagy in lipid metabolism during hepatocellular carcinoma (HCC) progression remains largely unexplored. Through integrated analysis of TCGA, MsigDB, FerrDb, and HADb datasets, we identified 33 ferroptosis and autophagy-dependent lipid metabolism-related genes (Fer-Aut-LMRGs) with prognostic significance. A novel two-gene (TXNRD1 and ALAS1) prog...

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Literature Corpus work
aae9c812-899a-5aba-acca-1ac7b6f49e06
DOI
10.21203/rs.3.rs-6502562/v1
Open publication

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