Identification of a novel signature derived from ferroptosis-related genes to predict prognosis, immune landscape and chemotherapeutic sensitivity in head and neck squamous cell carcinoma.

Abstract excerpt

BACKGROUND: Ferroptosis resistance is increasingly appreciated as an indispensable factor for tumor initiation, progression, and therapeutic resistance in various human malignancies including head and neck squamous cell carcinoma (HNSCC). Herein, we sought to develop a novel signature utilizing ferroptosis-related genes (FRGs) for prognosis and therapeutic prediction in HNSCC. METHODS: A prognostic signature...

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