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Target-enriched metagenomics-informed qPCR detects rare, potentially dangerous β-lactamase genes in wastewater

2025-07-22

Abstract excerpt

The rapid emergence of novel antibiotic resistance genes (ARGs) decreases the effectiveness of empirical antibiotic treatment for pathogen infections. Environmental ARG surveillance is an early-warning approach that can better inform antibiotic usage. Quantitative polymerase chain reaction (qPCR) is widely used for ARG surveillance because qPCR is easy, fast, and highly sensitive. However, it can only identify DNA...

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Literature Corpus work
aa83a68e-a50b-572e-9572-dbdedf68f771
DOI
10.1101/2025.07.21.665820
Open publication

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Target-enriched metagenomics-informed qPCR detects rare, potentially dangerous β-lactamase genes in wastewaterDOI 10.1101/2025.07.21.665820
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