Article

SHaploseek: A sequencing-only high-resolution implementation of comprehensive preimplantation genetic testing

2023-06-10

Abstract excerpt

<h4>Purpose</h4> We previously developed Haploseek, a clinically-validated, variant-agnostic comprehensive preimplantation genetic testing (PGT) solution. Haploseek is based on microarray genotyping of the embryo’s parents and relatives, combined with low-pass sequencing of the embryos. Here, to increase throughput and versatility, we aimed to develop a sequencing-only implementation of Haploseek. <h4>Methods</h4>...

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Literature Corpus work: aa80831c-dedb-5ee8-85d3-8d239f49c408
DOI: 10.1101/2023.06.06.23291016

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