Integrative models of the heart: achievements and limitations

Abstract excerpt

The recently completed draft sequence of the human genome provides access to a vast database of information, containing of the order of 30 000–40 000 genes. These are understood to encode some 250 000 proteins. Understanding how the information in the genome is used to create this ‘proteome’ is a major challenge, not least because predicting the functionally important three–dimensional structure of proteins from t...

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• Cardiac electrophysiology and arrhythmias
• Receptor Mechanisms and Signaling

Identifiers and source

Literature Corpus work

a9ddbc46-9360-5b0b-907f-84c22d7f1473

DOI

10.1098/rsta.2001.0816