Article

Distinct Pathway Activities are Associated with Prognosis and Response to Bortezomib- containing Treatment in MCL1-M Based Molecular Subtypes of Multiple Myeloma

2024-03-05

Abstract excerpt

<title>Abstract</title> Multiple myeloma (MM) is the second most prevalent hematological malignancy and remains incurable with remarkable heterogeneity in prognosis and treatment response across the patients. Clinical diagnosis and the existing molecular classification systems are inadequate for predicting treatment responses. Based on the convergence between plasma cell development and MM pathogenesis, we ide...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a942d704-0fd3-5cdb-b0bb-263f70808b35
DOI: 10.21203/rs.3.rs-3995303/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Distinct Pathway Activities are Associated with Prognosis and Response to Bortezomib- containing Treatment in MCL1-M Based Molecular Subtypes of Multiple MyelomaDOI 10.21203/rs.3.rs-3995303/v1Read

A gene expression signature based on cell-death related gene expression in multiple myelomaSemantic proximity Read

KRAS/NRAS Mutation-Associated Transcriptional Dysregulation Identifies NRL, CREM and IL-6 as Candidate Prognostic Biomarkers in Multiple MyelomaSemantic proximity Read

Genome-Wide Identification of Potential Biomarkers in Multiple Myeloma Using Meta-Analysis of mRNA and miRNA Expression DataSemantic proximity Read

A novel ferroptosis-related gene signature for predicting prognosis in multiple myelomaSemantic proximity Read

Revised International Staging System (R-ISS) stage-dependent analysis uncovers oncogenes and potential immunotherapeutic targets in multiple myeloma (MM)Semantic proximity Read

Revised International Staging System (R-ISS) stage-dependent analysis uncovers oncogenes and potential immunotherapeutic targets in multiple myelomaSemantic proximity Read

Identification of candidate therapeutics and signaling pathways for multiple myelomaSemantic proximity Read

A single-cell atlas characterizes dysregulation of the bone marrow immune microenvironment associated with outcomes in multiple myelomaSemantic proximity Read

Single cell RNA-seq data and bulk gene profiles reveal a novel signature of disease progression in multiple myelomaSemantic proximity Read

Chemogenomics Mapping of Potential Drugs and Targets for Treatment of Multiple MyelomaSemantic proximity Read

Characterization of driver mutations identifies gene signatures predictive of prognosis and treatment sensitivity in multiple myeloma.Semantic proximity Read

A novel prognostic model based on pyroptosis-related genes for multiple myelomaSemantic proximity Read