Article

Challenges in the Biotechnological Implementation of Oral RNA Interference as an Antiviral Strategy in <i>Aedes aegypti</i>

2023-11-05

Abstract excerpt

Mosquitoes, particularly Aedes aegypti , are critical vectors for globally significant pathogenic viruses. This study examines the limitations of oral RNA interference (RNAi) as a strategy to disrupt viral transmission by Ae. aegypti . We hypothesized that double-stranded RNA (dsRNA) targeting the Zika virus (ZIKV) or chikungunya virus (CHIKV) genomes produced by engineered bacterial symbionts could trigger an a...

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Literature Corpus work: a8d83c25-1264-5bf4-997e-88a4a869b32f
DOI: 10.1101/2023.11.05.565667

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