Article

TiSAn: Estimating Tissue Specific Effects of Coding and Noncoding Variants

2017-05-24

Abstract excerpt

Measures of general deleteriousness, like CADD or PolyPhen, have become indispensable tools in the interpretation of genetic variants. However, these measures say little about where in the organism these deleterious effects will be most apparent. An additional, complementary measure is needed to link deleterious variants (as determined by e.g., CADD) to tissues in which their effect will be most meaningful. Here,...

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Literature Corpus work: a8c0aff8-2286-5424-a373-6e8063590358
DOI: 10.1101/141408

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