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Comparison of metagenomic and targeted methods for sequencing human pathogenic viruses from wastewater

25 Oct 2023

Abstract excerpt

ABSTRACT Wastewater-based epidemiology is a powerful tool for monitoring the emergence and spread of viral pathogens at the population scale. Typical polymerase chain reaction (PCR)-based methods of quantitative and genomic monitoring of viruses in wastewater provide high sensitivity and specificity. However, these methods are limited to the surveillance of target viruses in a single assay and require prior...

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PMID: 37877702
DOI: 10.1128/mbio.01468-23

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