Article

The protective effect of crocin against paclitaxel-induced neurotoxicity

2025-03-17

Abstract excerpt

<title>Abstract</title> <p>Paclitaxel-based chemotherapy is an important treatment option. However, paclitaxel is known to have neurotoxic side effects. This study investigated the neuroprotective effect of crocin against paclitaxel-induced neurotoxicity in human SH-SY5Y neuroblastoma cell lines. A series of tests were performed to assess aspects such as cell viability, oxidative stress, genotoxicity, and apoptos...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a81b7f9f-1f35-5552-8d37-d6d14590fe86
DOI: 10.21203/rs.3.rs-6194558/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The protective effect of crocin against paclitaxel-induced neurotoxicityDOI 10.21203/rs.3.rs-6194558/v1Read

Role of crocin in several cancer cell lines: An updated review.Semantic proximity Read

Comparative Cytotoxic and Apoptotic Effects of drugs Compounds on Human Cell LinesSemantic proximity Read

An In Vitro Study of Saffron Carotenoids: The Effect of Crocin Extracts and Dimethylcrocetin on Cancer Cell LinesSemantic proximity Read

Synergistic Effects of Apigenin and Paclitaxel on Apoptosis of Cancer CellsSemantic proximity Read

Phyllanthus muellerianus and Ficus exasperata exhibit anti-proliferative and pro-apoptotic activities in human prostate cancer PC-3 cells by modulating calcium influx and activating caspasesSemantic proximity Read

Nanonoscapine: A Promising Treatment for Prostate Cancer Through Targeting GLI1 and BAX ExpressionSemantic proximity Read

Anti-Neuropathic Pain Activity of A Cationic Palladium (II) Dithiocarbamate By Suppressing The Inflammatory Mediators in Paclitaxel-Induced Neuropathic Pain ModelSemantic proximity Read

Natural Borneol Enhances Paclitaxel‐Induced Apoptosis of ESCC Cells by Inactivation of the PI3K/AKTSemantic proximity Read

Efficacy of Nano-Formulated Nitazoxanide Compared to Bulk Powder Against Human Oral Squamous Cell Carcinoma Cell lineSemantic proximity Read

A comprehensive review on anticancer mechanisms of the main carotenoid of saffron, crocinSemantic proximity Read

Cytotoxic Properties of Cyclophosphamide: A Focus on Its Mechanistic Impacts on Male Gonadal FunctionsSemantic proximity Read

Cytotoxicity and apoptotic activities of alpha-, gamma- and delta-tocotrienol isomers on human cancer cellsSemantic proximity Read