Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Engineering a bivalent nanoparticle vaccine with PCV2 capsid protein and PRRSV epitopes

12 Jun 2025

Abstract excerpt

BACKGROUND: Coinfection with multiple viruses is a common occurrence in the pig industry. Porcine reproductive and respiratory syndrome virus (PRRSV) and porcine circovirus type 2 (PCV2) are two significant pathogens, with a notable prevalence of their coinfection observed in clinical settings. However, reports on corresponding combination vaccines against PRRSV and PCV2 are scarce. The capsid (Cap) protein...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Virus Infections Studies
Share to SARS-CoV-2 and COVID-19 Research
Share to Viral Infectious Diseases and Gene Expression in Insects

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40506710
DOI: 10.1186/s12951-025-03514-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Engineering a bivalent nanoparticle vaccine with PCV2 capsid protein and PRRSV epitopesPMID 40506710Read ↗

Immunogenicity and Immunoprotection of PCV2 Virus-like Particles Incorporating Dominant T and B Cell Antigenic Epitopes Paired with CD154 Molecules in Piglets and MiceSemantic proximity Read ↗

Displaying epitope B and epitope 7 of porcine reproductive and respiratory syndrome virus on virus like particles of porcine circovirus type 2 provides partial protection to pigsSemantic proximity Read ↗

Bivalent circular RNA vaccines against porcine epidemic diarrhea virus and transmissible gastroenteritis virusSemantic proximity Read ↗

PCV Cap proteins fused with calreticulin expressed into polymers in Escherichia coli with high immunogenicity in miceSemantic proximity Read ↗

Porcine Circovirus (PCV) Genotype 2d-Based Virus-like Particles (VLPs) Induced Broad Cross-Neutralizing Antibodies against Diverse Genotypes and Provided Protection in Dual-Challenge Infection of a PCV2d Virus and a Type 1 Porcine Reproductive and Respiratory Syndrome Virus (PRRSV)Semantic proximity Read ↗

Two-Component Nanoparticle Vaccine Displaying Glycosylated Spike S1 Domain Induces Neutralizing Antibody Response against SARS-CoV-2 VariantsSemantic proximity Read ↗

Self-assembly of virus-like particles of porcine circovirus type 2 capsid protein expressed from Escherichia coliSemantic proximity Read ↗

Structure, Antigenic Properties, and Highly Efficient Assembly of PCV4 Capsid ProteinSemantic proximity Read ↗

Structural roles of PCV2 capsid protein N-terminus in PCV2 particle assembly and identification of PCV2 type-specific neutralizing epitopeSemantic proximity Read ↗

Efficacy of a novel antigen-decorated adenoviral vaccine platform against porcine respiratory coronavirus infection in a large natural hostSemantic proximity Read ↗

Efficacy test of a plant-based porcine circovirus type 2 (PCV2) virus-like particle vaccine against four PCV2 genotypes (2a, 2b, 2d, and 2e) in pigs.Semantic proximity Read ↗

Epitopes screening and vaccine molecular design of PEDV S protein based on immunoinformaticsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.