Article
Sorafenib in Molecularly Selected Cancer Patients: Final Analysis of the MOST-Plus Sorafenib Cohort
2023-05-15
Abstract excerpt
<h4>Background: </h4> MOST-plus is a multicenter, randomized, open-label, adaptive Phase II trial evaluating the clinical benefit of targeted treatments matched to molecular alteration in advanced/metastatic solid tumors. Sorafenib was tested on patients with tumors harboring sorafenib-targeted genes Methods: The MOST-plus trial used a randomized discontinuation design. After 12 weeks of sorafenib (400 mg, po BID)...
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Identifiers and source
- Literature Corpus work
- a74adf78-5dfe-5d44-8310-175c20fd08b7
- DOI
- 10.20944/preprints202305.1052.v1
