Article

Bacteriophage density influences the rate of resistance evolution

2025-10-05

Abstract excerpt

The antagonistic relationship between bacteria and bacteriophages (phages) drives genetic changes that result in phage resistance. Phage resistance mutations arise in natural microbial communities and during the treatment of diseases with phages (phage therapy), making it important to understand the dynamics of resistance acquisition. It is well-established that when bacteria are challenged with phages in dense li...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a73fd068-efe1-5f5f-bc51-1d7877a412a1
DOI: 10.1101/2025.10.05.680490

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Bacteriophage density influences the rate of resistance evolutionDOI 10.1101/2025.10.05.680490Read

The impact of phage and phage resistance on microbial community dynamics.Semantic proximity Read

Fitness Trade-Offs Resulting from Bacteriophage Resistance Potentiate Synergistic Antibacterial Strategies.Semantic proximity Read

<strong>The Ecology of Phage Resistance: </strong><strong>The Key to Successful Phage Therapy?</strong>Semantic proximity Read

Parasite diversity drives rapid host dynamics and evolution of resistance in a bacteria-phage system.Semantic proximity Read

Modeling multiphage-bacteria kinetics to predict phage therapy potency and longevitySemantic proximity Read

Greater Phage Genotypic Diversity Constrains Arms-Race Coevolution.Semantic proximity Read

Phage-induced diversification improves host evolvability.Semantic proximity Read

The impact of phage and phage resistance on microbial community dynamicsSemantic proximity Read

Modelling phage-bacteria interactions driving predation and horizontal gene transferSemantic proximity Read

Modelling the synergistic effect of bacteriophage and antibiotics on bacteria: killers and drivers of resistance evolutionSemantic proximity Read

Ecological conditions determine extinction risk in co-evolving bacteria-phage populations.Semantic proximity Read

Eco-evolutionary feedbacks shape the evolution of constitutive and inducible defencesSemantic proximity Read