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Discovery of intestinal mRNA expression profiles correlated with mucosal healing of ustekinumab patients with Crohn’s disease: bioinformatics analysis and prospective cohort validation

2024-04-12

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<title>Abstract</title> <p>Background: Variations existed in responses to ustekinumab (UST) treatment in patients with Crohn's disease (CD), but the underlying cause remains unknown. Our objective was to investigate the involvement of immune cells and identify potential biomarkers that can predict the response to IL 12/23 inhibitors in patients with CD. <h4>Methods:</h4> GSE207022 dataset was analyzed, which con...

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Literature Corpus work
a6c2a3ff-67d9-5d23-8ec9-d898a93ef663
DOI
10.21203/rs.3.rs-4135542/v1
Open publication

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Discovery of intestinal mRNA expression profiles correlated with mucosal healing of ustekinumab patients with Crohn’s disease: bioinformatics analysis and prospective cohort validationDOI 10.21203/rs.3.rs-4135542/v1
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