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Article

Tissue fixation effects on human retinal lipid analysis by MALDI imaging and LC-MS/MS technologies

2021-04-30

Abstract excerpt

<h4>ABSTRACT</h4> Imaging mass spectrometry (IMS) allows the location and abundance of lipids to be mapped across tissue sections of human retina. For reproducible and accurate information, sample preparation methods need to be optimized. Paraformaldehyde fixation of a delicate multilayer structure like human retina facilitates the preservation of tissue morphology by forming methylene bridge cross-links between...

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Literature Corpus work
a6713e0a-ba4c-558b-b16d-eb60da05631a
DOI
10.1101/2021.04.29.442044
Open publication

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Tissue fixation effects on human retinal lipid analysis by MALDI imaging and LC-MS/MS technologiesDOI 10.1101/2021.04.29.442044
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