Article

Physiological Expression Mapping in Cardiometabolic Disease: A State-Space Framework with Clinical and Hemodynamic Evidence

2026-03-26

Abstract excerpt

Contemporary clinical medicine relies on a risk-factor paradigm in which individual diseases are managed using population-derived thresholds. This reductionist approach is increasingly limited in cardiometabolic multimorbidity, where abnormalities arise from interacting dysregulations across cardiovascular, metabolic, renal, and endocrine systems, and interpretation of patient condition often requires an organism-...

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Literature Corpus work: a66b6cf1-9626-5ed2-a58f-6dd2d98b4002
DOI: 10.20944/preprints202603.2071.v1

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