Article

SILAKin: A novel high throughput SILAC and mass spectrometry-based assay to identify the substratome of kinases secreted by pathogens

2021-05-05

Abstract excerpt

<h4>ABSTRACT</h4> Protein phosphorylation is one of the most important reversible post-translational modifications. It affects every cellular process including differentiation, metabolism and cell cycle. Eukaryotic protein kinases (ePK) catalyse the transfer of a phosphate from ATP onto proteins, which regulates fast changes in protein activity, structure or subcellular localisation. The systematic identification...

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Literature Corpus work: a60907c5-8cbe-5d2a-9b14-156ee4a83bf6
DOI: 10.1101/2021.05.05.442720

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