Article

Urinary Proteome Profiling by Several Methods, Identifies Titin as the Most-Differentiating Noninvasive Urinary Biomarker of Disease Severity in Becker Muscular Dystrophy

2026-08-04

Abstract excerpt

<h4>Background: </h4> Becker’s muscular dystrophy (BMD) is a clinically heterogeneous dystrophinopathy caused by in-frame mutations in the dystrophin gene, resulting in variable disease severity. This variability limits the effectiveness of standardized functional measures for tracking progression. Circulating biomarkers, including urinary titin fragments generated during muscle injury, offer a promising noninvasi...

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Literature Corpus work: a6035ea1-3975-5007-9d98-9fd701dccbb8
DOI: 10.20944/preprints202608.0137.v1

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