Back to search

Article

The MUSCLE-GLP1-CKD study: design and rationale of a prospective real-world cohort evaluating muscle health during GLP-1 receptor agonist therapy in chronic kidney disease and type 2 diabetes

2026-07-23

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> Sarcopenia and impaired physical function are clinically relevant complications of chronic kidney disease (CKD). Patients with CKD and type 2 diabetes mellitus (T2DM) are particularly vulnerable to muscle impairment because of insulin resistance, inflammation, obesity, nutritional abnormalities, multimorbidity and reduced physical activity. Glucagon-like pepti...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
a5ef2ba9-0d71-55aa-a9d3-cbcfc37ac11f
DOI
10.21203/rs.3.rs-10372706/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
The MUSCLE-GLP1-CKD study: design and rationale of a prospective real-world cohort evaluating muscle health during GLP-1 receptor agonist therapy in chronic kidney disease and type 2 diabetesDOI 10.21203/rs.3.rs-10372706/v1
Chronic Kidney Disease and Sarcopenia: A Qualitative Review of the Role of the Psoas Muscle MeasurementSemantic proximity
Sarcopenic obesity and body composition phenotypes in older adults with chronic kidney disease: associations with estimated mortality risk.Semantic proximity
Sarcopenic Obesity Accelerates the Progression of Cardiovascular-Kidney-Metabolic Syndrome: A Longitudinal Discovery and Cross-Sectional Validation StudySemantic proximity
Muscle Mass and Muscle Strength in Non-Dialysis Dependent Chronic Kidney Disease PatientsSemantic proximity
Exercise as targeted therapy in type 2 diabetes: a phenotype-informed clinical prioritisation framework for adapted physical activity.Semantic proximity
Multidimensional nutritional and body-composition phenotypes and their associations with prevalent anaemia and metabolic abnormalities in CKD: protocol for an EHR-based retrospective baseline cross-sectional study with a prospective measurement extension.Semantic proximity
Physical Activity In Renal Disease (PAIRED) and the effect on hypertension: study protocol for a randomized controlled trialSemantic proximity
The response of the skeletal muscle transcriptome to exercise in chronic kidney diseaseSemantic proximity
No Evidence of Causal Effects between Renal Impairment and Muscle Wasting: a Two-Sample Mendelian Randomization StudySemantic proximity
Depot-Specific Cardiorenal Adipose Remodeling with SGLT2i in Chronic Kidney DiseaseSemantic proximity
Chronic kidney disease and high eGFR according to body composition phenotype in adults with normal BMI.Semantic proximity
Possible sarcopenia and risk of chronic kidney disease: a four-year follow-up study and Mendelian randomization analysisSemantic proximity
Select a neighboring publication to make it the new centre.