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Article

Universal method for the gentle isolation of intact microvessels from frozen tissue: a multiomic investigation into the neurovasculature

2023-05-11

Abstract excerpt

The neurovascular unit (NVU), comprised of endothelial cells, pericytes, smooth muscle cells, astrocytic endfeet and microglia together with neurons, is paramount for the proper function of the central nervous system. The NVU gatekeeps blood-brain barrier (BBB) properties which, as a system, experiences impairment in several neurological and psychiatric diseases, and contributes to pathogenesis. To better understa...

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Identifiers and source

Literature Corpus work
a580195d-86fb-54e4-a346-c9f319a2dcdb
DOI
10.1101/2023.05.10.540076
Open publication

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Universal method for the gentle isolation of intact microvessels from frozen tissue: a multiomic investigation into the neurovasculatureDOI 10.1101/2023.05.10.540076
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