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Integrative Analysis of Multi-Omics Data Identified klrc3 as Key Nodes in a Gene Regulatory Network Related to Immune Phenotypes in Lung Adenocarcinoma

2021-08-25

Abstract excerpt

In a recent study, the PD-1 inhibitor has been widely used in clinical trials and shown to improve various cancers. However, PD-1/PD-L1 inhibitors showed a low response rate and showed to be effective for a small number of cancer patients. Thus, it is important to identify key genes, which can enhance the PD-1/PD-L1 response for promoting immunotherapy. Here, we used ssGSEA and unsupervised clustering analysis to...

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Literature Corpus work: a5385f6e-9468-5c03-b08f-e2a93060988c
DOI: 10.20944/preprints202108.0366.v2

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