Article

Generation of human induced pluripotent stem cells from a patient with Beckwith-Wiedemann syndrome

2025-04-01

Abstract excerpt

<title>Abstract</title> <p>Beckwith-Wiedemann syndrome (BWS) is a human genomic imprinting disorder caused by an imprinting abnormality in the chromosome 11p15.5 region. It is rare and sporadic with unclear etiology and pathogenesis. We identified a family with a clustering of BWS cases. An induced pluripotent stem cell line (BWS iPSC) was generated from peripheral blood mononuclear cells (PBMCs) of one affected...

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Literature Corpus work: a4d63a87-6626-59a4-b503-70d076fbf44e
DOI: 10.21203/rs.3.rs-5034318/v1

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