Article

Evaluation of the Main Regulators of Systemic Iron Homeostasis in Pyruvate Kinase Deficiency

2022-11-23

Abstract excerpt

Iron homeostasis and dyserythropoiesis are poorly investigated in pyruvate kinase deficiency (PKD), the most common glycolytic defect of erythrocytes. Herein, we studied the main regulators of iron balance and erythropoiesis, as soluble transferrin receptor (sTfR), hepcidin, erythroferrone (ERFE), and erythropoietin (EPO), in a cohort of 41 PKD patients, compared with 42 affected by congenital hemolytic anemia typ...

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Literature Corpus work: a47966c8-10aa-5ea0-bf01-0f435afcad90
DOI: 10.21203/rs.3.rs-2276698/v1

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