Article

A long-acting prolactin to combat lactation insufficiency

2023-12-15

Abstract excerpt

Human infants are born to breastfeed. While 50% of lactating persons struggle to make enough milk, there are no governmentally-approved drugs to enhance lactation 1 . Here, we engineer a variant of the naturally-occurring driver of lactation, the hormone Prolactin, to increase its serum half-life and produce a viable drug candidate. Our engineered variant, Prolactin-eXtra Long-acting (Prolactin-XL), is comprised...

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Literature Corpus work: a434cde4-d0e8-56f0-bcdd-b5302cbe78c3
DOI: 10.1101/2023.12.15.571886

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