Article
Urine-derived exosomes from individuals with IPF carry pro-fibrotic cargo
2022-05-06
Abstract excerpt
<h4>Background</h4> MicroRNAs (miRNA) and other components contained in extracellular vesicles may reflect the presence of a disease. Lung tissue, sputum and sera of individuals with idiopathic pulmonary fibrosis (IPF) show alterations in miRNA expression. We designed this study to test whether urine and/or tissue derived exosomal miRNAs from individuals with IPF carry cargo that can promote fibrosis. <h4>Methods...
Topics
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- Air Quality and Health Impacts
- Extracellular vesicles in disease
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Medical Imaging and Pathology Studies
- Occupational and environmental lung diseases
- Occupational exposure and asthma
- Pulmonary Hypertension Research and Treatments
- Systemic Sclerosis and Related Diseases
Identifiers and source
- Literature Corpus work
- a2d29b87-443d-5d3c-bbbd-6fc191180285
- DOI
- 10.1101/2022.05.06.490876
