Article

Reliable variant calling during runtime of Illumina sequencing

2018-08-09

Abstract excerpt

The sequential paradigm of data acquisition and analysis in next-generation sequencing leads to high turnaround times for the generation of interpretable results. We combined a novel real-time read mapping algorithm with fast variant calling to obtain reliable variant calls still during the sequencing process. Thereby, our new algorithm allows for accurate read mapping results for intermediate cycles and supports...

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Identifiers and source

Literature Corpus work: a2aeab89-39cb-5e4a-838a-61fd1a6adefe
DOI: 10.1101/387662

Open publication

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