Article
Nasal microbionts differentially colonize and elicit cytokines in human nasal epithelial organoids
2024-09-25
Abstract excerpt
<h4>ABSTRACT</h4> Nasal colonization by Staphylococcus aureus or Streptococcus pneumoniae is associated with an increased risk of infection by these pathobionts, whereas nasal colonization by Dolosigranulum species is associated with health. H uman n asal epithelial o rganoids (HNOs) physiologically recapitulate human nasal respiratory epithelium with a robust mucociliary blanket. We reproducibly monocoloni...
Topics
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- Antimicrobial Resistance in Staphylococcus
- Bacterial biofilms and quorum sensing
- Microbial infections and disease research
- Oral microbiology and periodontitis research
- Otolaryngology and Infectious Diseases
- Pneumonia and Respiratory Infections
- Respiratory viral infections research
- Sinusitis and nasal conditions
Identifiers and source
- Literature Corpus work
- a28aec64-6cba-5712-9fd1-a980c5071f1c
- DOI
- 10.1101/2024.09.25.614934
