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Integrated Multi-Omics Profiling Maps Ferroptosis–Cuproptosis Diversity in Cervical Cancer and Identifies a PDGFRB-Driven Monocyte Fibrotic Program Targeted by Sorafenib

2026-02-10

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<title>Abstract</title> <p>Background: Ferroptosis and cuproptosis are two distinct forms of metal-dependent regulated cell death that have emerged as important mechanisms in tumor biology. However, the crosstalk between these pathways and their clinical relevance in cervical cancer remain largely unexplored. <h4>Methods:</h4> Using the TCGA-CESC cohort (n = 304), we quantified ferroptosis- and cuproptosis-relate...

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Literature Corpus work
a23ee1a1-1983-58a8-9079-7918382701ac
DOI
10.21203/rs.3.rs-8811979/v1
Open publication

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Integrated Multi-Omics Profiling Maps Ferroptosis–Cuproptosis Diversity in Cervical Cancer and Identifies a PDGFRB-Driven Monocyte Fibrotic Program Targeted by SorafenibDOI 10.21203/rs.3.rs-8811979/v1
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