Back to search

Article

In (deficit) schizophrenia, a general cognitive decline (G-CoDe) partly mediates the effects of neuro-immune and neuro-oxidative toxicity on the symptomatome and quality of life

2021-04-06

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> Schizophrenia and deficit schizophrenia are accompanied by neurocognitive impairments. The aim of this study was to examine whether a general factor underpins impairments in key Cambridge Neuropsychological Test Automated Battery (CANTAB) probes, verbal fluency (VFT), world list memory (WLM), true recall, and Mini Mental State Examination (MMSE). <h4>Methods</h4> We recruited 8...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
a2023e8c-877d-534a-8c02-b4e1a9b91b8d
DOI
10.1101/2021.03.29.21254523
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
In (deficit) schizophrenia, a general cognitive decline (G-CoDe) partly mediates the effects of neuro-immune and neuro-oxidative toxicity on the symptomatome and quality of lifeDOI 10.1101/2021.03.29.21254523
A Generalized Cognitive Decline (GCoDe) Partly Mediates the Effects of Neuro-Immune and Neuro-Oxidative Toxicity on the Symptomatome and Lowered Quality of Life in (Deficit) SchizophreniaSemantic proximity
A unified general cognitive factor explains impairment across schizophrenia, bipolar disorder, OCD and substance use disorderSemantic proximity
Lowered Antioxidant Defenses and Increased Oxidative Toxicity Are Hallmarks of Deficit Schizophrenia: Neurocognitive and Symptom CorrelatesSemantic proximity
The general neurocognitive decline in patients with methamphetamine (MA) use and transient MA-induced psychosis is primarily determined by oxidative and AGE-RAGE stressSemantic proximity
In schizophrenia, the effects of the IL-6/IL-23/Th17 axis on health-related quality of life and disabilities are partly mediated by generalized cognitive decline and the symptomatomeSemantic proximity
The novel pathway phenotype “major neurocognitive psychosis” is validated as a distinct class through the analysis of immune-linked neurotoxicity biomarkers and neurocognitive deficitsSemantic proximity
The negative symptoms of schizophrenia: lessons from a precision nomothetic psychiatry approachSemantic proximity
Construction of a Neuro-Immune-Cognitive Pathway-Phenotype Underpinning the Phenome of Deficit Schizophrenia.Semantic proximity
Construction of a Neuro-Immune-Cognitive Pathway-Phenotype Underpinning the Phenome of Deficit SchizophreniaSemantic proximity
The interleukin-6/interleukin-23/Thelper-17-axis as a driver of neuro-immune toxicity in the major neurocognitive psychosis or deficit schizophrenia: a precision nomothetic psychiatry analysisSemantic proximity
Cognitive deficits in clinical high risk, genetically at high-risk for psychosis and patients with first-episode schizophreniaSemantic proximity
The Differences in Cognitive Deficits Among Older Adult Patients with Schizophrenia, Schizoaffective Disorder, and Bipolar Disorder: The Results of a Chart Review Study From 1997 to 2017Semantic proximity
Select a neighboring publication to make it the new centre.