Article

Regnase-1 Promotes Tumor-Initiating Activity in Non-Small Cell Lung Cancer

2025-07-11

Abstract excerpt

Regnase-1, encoded by the ZC3H12A gene, is a well-known RNase that suppresses inflammation by degrading the mRNAs of inflammatory cytokines. However, its role in cancer pathogenesis, especially in non-small cell lung cancer (NSCLC), remains poorly understood. Through an analysis of public databases, we found that NSCLC patients with higher ZC3H12A expression levels had a worse prognosis than those with lower lev...

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Literature Corpus work: a1e70d81-1fd3-5e67-a99c-b69b5c5d1adb
DOI: 10.1101/2025.07.08.663650

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