Article

Spectrum of Genetic Variants Associated with Maple Syrup Urine Disease in the Middle East and North Africa (MENA) Region: A Systematic Review

2024-03-05

Abstract excerpt

<title>Abstract</title><p><bold>Background:</bold>Maple syrup urine disease (MSUD) is a hereditary metabolic disorder caused by a deficiency in the branched-chain α-keto acid dehydrogenase (BCKD) enzymatic complex. The Middle East and North Africa (MENA) region has witnessed a significant rise in the prevalence of MSUD due to high rates of consanguinity. Despite numerous genetic association studies, the complex re...

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Literature Corpus work: a1cdc35c-6dcb-568f-aff6-11dad235071f
DOI: 10.21203/rs.3.rs-3944099/v1

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