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The Hyaluronan-Related Genes HAS2, HYAL1-5, HYALP1 are Associated with Prognosis, Cell Viability and Spheroid Formation Capacity in Ovarian Cancer

2021-12-21

Abstract excerpt

<title>Abstract</title> <p><bold>Purpose:</bold> Hyaluronan modulates tumor progression, including cell adhesion, cohesion, proliferation and invasion, and the cancer stem cell phenotype. In ovarian cancer, high levels of stromal hyaluronan are associated with poor prognosis. In this work hyaluronan synthases (HAS1-3) and hyaluronidases (HYAL1-5, HYALP1) were examined with regard to different levels of gene expre...

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Literature Corpus work
a0b2a63e-8c1e-5cf2-853d-df6f7b023bab
DOI
10.21203/rs.3.rs-1180717/v1
Open publication

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